Wow, this is turning out to be an interesting conference ( I also got a really cool conference bag: a clear plastic bag...)
Scoble has a really interesting post on the conference http://scobleizer.wordpress.com/2006/03/20/microsoft-too-business-oriented-to-get-web-20/
He just recently mentioned the classic focus group $100 question by Don Box on how to make current technologies more accessible.
Lets hope MIX06 also mekes this happen. Whats the use of having huge heavy frameworks if you cannot make things happen in a jiffy...
On the way here I thought very hard about the sucking down post by Guy Kawasaki
Take a look