There is no magic fairy dust protecting Macs - Dai Zovi, security researcher and co-author of The Mac Hacker's Handbook.
Umm, no - so, please, those of you who are saying "use Firefox" to avoid the scareware, please stop.
http://commercial-archive.com/node/136476
What about Firefox with the NoScript extension?
Firefox may be safer with the NoScript extension, but so is IE if you turn off scripting. It's horses for courses - in fact, IE could be said to be preferable because you don't need to go out and find an extension to turn off scripting. In any event, my focus is what happens to users running their browsers with default settings, and no extra protections. Invariably the advice I see given is 'use Firefox', not 'use Firefox, oh and don't forget to install NoScript, and make sure you patch, oh and don't forget about all those third party applications out there that are being targeted - Quicktime, Java, etc'.
Well, you can always turn off Javascript, Java, etc. in Firefox without any extensions. But NoScript lets you selectively block scripting to specific sites. Pretty handy.
Firefox with Adblock Plus also blocks this.