Possible fixes for crashes caused by MS06-042 (KB918899)
Note: An new version of 918899 was planned for release by 22 August for **IE6 SP1** users. Unfortunately, an issue with the new version has forced the delay of the updated patch for a few days, but it has now been released.
I am very grateful for, and indebted to, some pretty amazing people and resources that actively share information about problems with patches and security issues. Its thanks to those resources that I am able to pass on information such as that in this post which has been combined from information in a couple of lists, one security focused, one related to patch management ..... so thanks all 
There are reports of MS06-042 causing crashes when PeopleSoft is installed. One noted crash involves 0xC0000005 in NTDLL.DLL
Affected OS listed in the KB are IE6SP1 installations on the following operating systems:
Microsoft Windows XP Professional (SP1 only?)
Microsoft Windows XP Home Edition (SP1 only?)
Microsoft Windows 2000 Professional Edition (???)
Microsoft Windows 2000 Service Pack 4
Microsoft Windows 2000 Advanced Server (???)
The fix for people using PeopleSoft, taken from the windows.update newsgroup, is:
In PIA, navigate to "PeopleTools -> Web Profile -> Web Profile Configurations". Search for your webprofile. In the "General" tab, uncheck the following:
Compress Responses = unchecked
Compress Response References = unchecked
Compress Query = unchecked [If you have PT8.44, please ignore since Compress Query does exist in PT8.44]
Save your webprofile changes and you must bounce your PIA.
Another suggested fix is to disable "Use HTTP 1.1" via IE Tools, Internet Options, Advanced Tab:
Note, a hotfix is available if this fixes your problem. Internet Explorer 6 Service Pack 1 unexpectedly exits after you install the 918899 update
http://support.microsoft.com/kb/923762/en-us
Sage CRM and CA Unicentre users - try the workaround and the hotfix - do not uninstall the patch unless you have no other alternative (SAGE... you need to work out the difference between a PATCH and a SERVICE PACK) (SANS - why are you not suggesting the workaround or hotfix instead of install IE7, uninstall the patch, or use a different browser???)
Another suggested fix is to uninstall MS06-042, edit the registry to ensure the following key exists, reinstall MS06-042, then reboot:
[HKEY_LOCAL_MACHINE\Software\Microsoft\Internet Explorer]
"QFEInstalled"=dword:00000001
The Technet article is here:
http://www.microsoft.com/technet/security/Bulletin/MS06-042.mspx
Good luck all, I hope this helps.