Nucleo 0.6 Released
The open source framework I created has been released for the 0.6 version, which includes:
Some AJAX control updates
New MVC helpers
An MVP framework agnostic to a specific environment (though with only an ASP.NET implementation at the moment, but more to come there).
Framework Plumbing updates/issue fixes
Several ways to develop custom AJAX components
Some Entity Framework Add-Ons (Optional)
Its available here: http://nucleo.codeplex.com/. I will follow up with documentation/screencasts. Please let me know what you think if you try it out.