Jet DB with IIS 6.0
This is a known issue and been pending for quite a while. Finaly it's out. This is actually a Jet bug and it HAS nothing to do with IIS 6.0, but due to the error only happens with IIS 6.0, it was 'assumed' that it is IIS fault :(
Go grab it -
838306 FIX: Web applications that use the Jet database engine may stop responding under heavy load